1.
EJMM-Egyptian Journal of Medical Microbiology [The]. 1992; 1 (2): 122-127
in English
| IMEMR
| ID: emr-23439
ABSTRACT
Twenty five rabbits were inoculated with HSV type [1] to estimate the humoral immune response and corneal protection. The serum neutralizing antibody could be detected 15 days after inoculation. Ig[G], Ig[A] and Ig[M] specific to the virus were detected by immunofluorescence. Only corneae of 2 out of 14 immunized rabbits developed corneal ulcers, when challenged with the virus, as compared to 5 non-immunized that developed ulcer. The 2 immunized rabbits that developed corneal ulcers showed complete healing in 3 days to treatment with trifluorotrhymidine as compared to 6 days for the non-immunized control group [5 rabbits]